How Does Malaria Penetrate the Cell Membrane?
Question by Shadow Warrior: How does malaria penetrate the cell membrane?
Does the cell mistake it for something good possibly?
Best answer:
Answer by TweetyBird
“How does malaria penetrate the cell membrane?” — Malaria doesn’t penetrate anything. Don’t make the mistake of confusing the parasite that causes malaria, Plasmodium, with the disease itself. Malaria in humans is caused by one or more of the four members of the genus Plasmodium. These four are Plasmodium falciparum, P. vivax, P. ovale, and P. malariae. The parasites have a life cycle of two stages, the sexual (sporogony) and asexual phases (schizogony). Durng the asexual phase, the Plasmodium is known as a schizont and during the sexual phase, a sporozoite.
Schizogony begins when an infective female anopheline mosquito injects sporozoites into the human host while taking a blood meal. The sporozoite stage of the parasite disappears from circulation within thirty minutes. Those avoiding the host’s immune system invade the liver and undergo development and multiplication to form schizonts. Over the next five to fifteen days, the schizonts mature, rupture the liver cell, and invade the circulation as merozoites. These merozoites bind to the red blood cell wall. They then penetrate the red blood cell, where they develop as ring forms and grow into trophozoites. Further division creates red blood cell merozoites which form a mature schizont. The blood cell swells and ruptures, releasing merozoites that go on to invade other red blood cells. When the red blood cells rupture, cellular debris from these infected cells is released into the blood and it’s the response by the immune system that causes the symptoms.
“Does the cell mistake it for something good possibly?” — Not at all.
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