Alcoholism: Genes Play Role in How Alcohol Affects Men and Women
Alcoholism: Genes Play Role in How Alcohol Affects Men and Women
New genetic research may help explain some of the different ways that alcoholism affects men and women.
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Alcoholism: Why the New Definition of Addiction, as “Brain Disease,” Falls Short
In 1964, the American Medical Association declared alcoholism a “disease.” Half a century later, the American Society of Addiction Medicine (ASAM) has proclaimed addiction, including alcoholism and “process” addictions like gambling, to be the same. According to the ASAM’s definition, … Continue reading ?
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Alcoholism: The aldehyde dehydrogenase-2 polymorphism affects alcohol dependence differently by gender
Gender differences exist in the prevalence, characteristics, and course of alcohol dependence (AD). Polymorphisms of alcohol dehydrogenase-1B (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) are strong genetic determinants of AD. While inactive ALDH2 traditionally delays the development of AD in men, a new study has found that inactive ALDH2 can accelerate the development of AD in women.
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Alcoholism: Linking brain-derived neurotrophic factor to alcohol dependence
( Alcoholism: Clinical & Experimental Research ) Brain-derived neurotrophic factor (BDNF) regulates neuronal plasticity. Researchers have found high serum BDNF levels among alcohol-dependent (AD) but abstinent individuals that do not correlate with either chronic drinking or associated toxicity.These findings suggest that BDNF may predict relapse in AD individuals undergoing treatment.
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Alcoholism: How excess alcohol depresses immune function
Alcoholism suppresses the immune system, resulting in a high risk of serious, and even life-threatening infections. A new study shows that this effect stems largely from alcohol’s toxicity to immune system cells called dendritic cells. These cells play a critical role in immune function, responding to danger signals by searching for unfamiliar antigens within the body that would be coming from …
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